Disease-gene associations mined from literature

Literature associating IL1RL1 and primary spontaneous pneumothorax

IL1RL1 [ENSP00000233954]

Interleukin 1 receptor-like 1; Receptor for interleukin-33 (IL-33); signaling requires association of the coreceptor IL1RAP. Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function; I-set domain containing

Synonyms:  IL1RL1,  IL1RL1p,  hIL1RL1,  A8VPW9,  A8VPX0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM