Literature associating DOK1 and chronic myeloid leukemia
Docking protein 1, 62kDa (downstream of tyrosine kinase 1); DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Synonyms: DOK1, DOK1p, hDOK1, Q2TA81, Q99704 ...