DISEASES

Disease-gene associations mined from literature

Literature associating NRBP1 and juvenile spinal muscular atrophy

NRBP1 [ENSP00000233557]

Nuclear receptor binding protein 1; May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Synonyms:  NRBP1,  NRBP1p,  hNRBP1,  C9JDW7,  C9JHZ6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM