Disease-gene associations mined from literature

Literature associating TFPI and alpha-2-plasmin inhibitor deficiency

TFPI [ENSP00000233156]

Tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.

Synonyms:  TFPI,  C9J103,  C9JBB3,  C9JKV3,  C9JP39 ...

Linkouts:  STRING  Pharos  UniProt  OMIM