DISEASES

Disease-gene associations mined from literature

Literature associating NEK4 and retinitis pigmentosa 23

NEK4 [ENSP00000233027]

Serine/threonine-protein kinase NRK2; Protein kinase that seems to act exclusively upon threonine residues (By similarity). Required for normal entry into proliferative arrest after a limited number of cell divisions, also called replicative senescence. Required for normal cell cycle arrest in response to double-stranded DNA damage.

Synonyms:  NEK4,  NEK4p,  hNEK4,  E7EX48,  F8WAX1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM