DISEASES

Disease-gene associations mined from literature

Literature associating CDX1 and bile reflux

CDX1 [ENSP00000231656]

Caudal-type homeobox protein 1; Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine; HOXL subclass homeoboxes

Synonyms:  CDX1,  CDX1p,  hCDX1,  P47902,  P47902p ...

Linkouts:  STRING  Pharos  UniProt  OMIM