Disease-gene associations mined from literature

Literature associating TRIM23 and mulibrey nanism

TRIM23 [ENSP00000231524]

ADP-ribosylation factor domain-containing protein 1; Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in 'Lys-63'-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit; In the C-terminal section; belongs to the small GTPase superfamily. Arf family.

Synonyms:  TRIM23,  TRIM23p,  hTRIM23,  D6R9E9,  D6RBN4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM