Disease-gene associations mined from literature

Literature associating IL4 and egg allergy

IL4 [ENSP00000231449]

Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types . It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages (By similarity). Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4 (By similarity).

Synonyms:  IL4,  IL4p,  hIL4,  D4HNR6,  P05112 ...

Linkouts:  STRING  Pharos  UniProt  OMIM