DISEASES

Disease-gene associations mined from literature

Literature associating LNPEP and choriocarcinoma

LNPEP [ENSP00000231368]

Insulin-regulated membrane aminopeptidase; Release of an N-terminal amino acid, cleaves before cysteine, leucine as well as other amino acids. Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy. May be involved in the inactivation of neuronal peptides in the brain. Cleaves Met-enkephalin and dynorphin. Binds angiotensin IV and may be the angiotensin IV receptor in the brain; Aminopeptidases

Synonyms:  LNPEP,  Q9UIQ6,  OTASE,  Q9UIQ6p,  hQ9UIQ6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM