Literature associating GRM6 and retinal disease
Glutamate receptor, metabotropic 6; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision; Glutamate metabotropic receptors
Synonyms: GRM6, GRM6p, hGRM6, O15303, GPRC1F ...