DISEASES

Disease-gene associations mined from literature

Literature associating LOX and autosomal recessive congenital ichthyosis

LOX [ENSP00000231004]

Protein-lysine 6-oxidase; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity); Belongs to the lysyl oxidase family.

Synonyms:  LOX,  B0AZT2,  B4DN04,  B7ZAJ4,  D0PNI2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM