DISEASES

Disease-gene associations mined from literature

Literature associating PAPD7 and nemaline myopathy 3

PAPD7 [ENSP00000230859]

TRAMP-like complex polyadenylate polymerase; Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post- transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation; Belongs to the DNA polymerase type-B-like family.

Synonyms:  PAPD7,  PAPD7p,  hPAPD7,  B4E0T3,  B7ZLL4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM