DISEASES

Disease-gene associations mined from literature

Literature associating GUCA1B and hereditary choroidal atrophy

GUCA1B [ENSP00000230361]

Guanylate cyclase activator 1B (retina); Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low, and GC1 and GC2 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure; EF-hand domain containing

Synonyms:  GUCA1B,  GUCA1Bp,  hGUCA1B,  Q9UMX6,  GCAP2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM