Disease-gene associations mined from literature

Literature associating IYD and goiter

IYD [ENSP00000229447]

Iodotyrosine dehalogenase 1; Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine; Belongs to the nitroreductase family.

Synonyms:  IYD,  C9JXJ9,  F5H543,  F6VN83,  H7C0X6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM