DISEASES

Disease-gene associations mined from literature

Literature associating IL26 and hidradenitis suppurativa

IL26 [ENSP00000229134]

Interleukin 26; May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin; Interleukins

Synonyms:  IL26,  IL26p,  hIL26,  Q9NPH9,  AK155 ...

Linkouts:  STRING  Pharos  UniProt  OMIM