DISEASES

Disease-gene associations mined from literature

Literature associating ZPR1 and muscular atrophy

ZPR1 [ENSP00000227322]

Zinc finger protein ZPR1; Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus. Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies. Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons. Plays a role in the splicing of cellular pre-mRNAs. May be involved in H(2)O(2)-induced neuronal cell death; Belongs to the ZPR1 family.

Synonyms:  ZPR1,  ZPR1p,  hZPR1,  B4DVT8,  F8WBC5 ...

Linkouts:  STRING  Pharos  UniProt