DISEASES

Disease-gene associations mined from literature

Literature associating SPI1 and salmonellosis

SPI1 [ENSP00000227163]

31 kDa-transforming protein; Binds to the PU-box, a purine-rich DNA sequence (5'- GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B- cells. Also binds RNA and may modulate pre-mRNA splicing (By similarity); Belongs to the ETS family.

Synonyms:  SPI1,  SPI1p,  hSPI1,  F5GZ94,  F5H3K6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM