DISEASES

Disease-gene associations mined from literature

Literature associating CD38 and IgG4-related disease

CD38 [ENSP00000226279]

2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system; Belongs to the ADP-ribosyl cyclase family.

Synonyms:  CD38,  CD38p,  hCD38,  B4DMR7,  CD38-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM