DISEASES

Disease-gene associations mined from literature

Literature associating P2RX1 and neurogenic bladder

P2RX1 [ENSP00000225538]

Purinergic receptor P2X, ligand-gated ion channel, 1; Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death (By similarity); Purinergic receptors P2X

Synonyms:  P2RX1,  P2RX1p,  hP2RX1,  D3DTJ7,  I3L3H3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM