Literature associating CYP26A1 and acute promyelocytic leukemia
Cytochrome P450, family 26, subfamily A, polypeptide 1; Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18- hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA; Belongs to the cytochrome P450 family.
Synonyms: CYP26A1, CYP26A1p, hCYP26A1, CYP26A1-001, CYP26A1-002 ...