Disease-gene associations mined from literature

Literature associating PLGRKT and congenital myasthenic syndrome 5

PLGRKT [ENSP00000223864]

Plasminogen receptor, C-terminal lysine transmembrane protein; Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metallproteinase activation, such as of MMP2 and MMP9.

Synonyms:  PLGRKT,  PLGRKT-001,  PLGRKT-002,  PLGRKT-003,  PLGRKT-004 ...

Linkouts:  STRING  Pharos  UniProt