Literature associating C5 and paroxysmal nocturnal hemoglobinuria
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled; C3 and PZP like, alpha-2-macroglobulin domain containing
Synonyms: C5, C5p, hC5, C5-001, C5-002 ...