Literature associating FIS1 and optic nerve disease
Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae); Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin- related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission; Belongs to the FIS1 family.
Synonyms: FIS1, FIS1p, hFIS1, C9JXH1, F5H509 ...