Disease-gene associations mined from literature

Literature associating SERPINE1 and severe pre-eclampsia

SERPINE1 [ENSP00000223095]

Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis; Serpin peptidase inhibitors

Synonyms:  SERPINE1,  A0A024QYT5,  B7Z1D9,  B7ZAB0,  P05121 ...

Linkouts:  STRING  Pharos  UniProt  OMIM