DISEASES

Disease-gene associations mined from literature

Literature associating HBP1 and early infantile epileptic encephalopathy 1

HBP1 [ENSP00000222574]

High mobility group box transcription factor 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

Synonyms:  HBP1,  HBP1p,  hHBP1,  A0A024R722,  B4DJ36 ...

Linkouts:  STRING  Pharos  UniProt