Literature associating HBP1 and early infantile epileptic encephalopathy 1
High mobility group box transcription factor 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.
Synonyms: HBP1, HBP1p, hHBP1, A0A024R722, B4DJ36 ...