Literature associating EPOR and essential thrombocythemia
Erythropoietin receptor; Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.
Synonyms: EPOR, I6R7G3, K7EN47, K7EP50, K7ERB5 ...