Disease-gene associations mined from literature

Literature associating EPOR and familial erythrocytosis 4

EPOR [ENSP00000222139]

Erythropoietin receptor; Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

Synonyms:  EPOR,  I6R7G3,  K7EN47,  K7EP50,  K7ERB5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM