Literature associating DKKL1 and rectum adenocarcinoma
Cancer/testis antigen 34; Involved in fertilization by facilitating sperm penetration of the zona pellucida. May promotes spermatocyte apoptosis, thereby limiting sperm production. In adults, may reduces testosterone synthesis in Leydig cells. Is not essential either for development or fertility.
Synonyms: DKKL1, DKKL1p, hDKKL1, DKKL1-001, DKKL1-002 ...