Literature associating TNFRSF10A and autoimmune disease of endocrine system
Tumor necrosis factor receptor superfamily, member 10a; Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B; CD molecules
Synonyms: TNFRSF10A, E5RFH1, F8U8C0, O00220, TNFRSF10A-001 ...