Disease-gene associations mined from literature

Literature associating TOX3 and estrogen-receptor positive breast cancer

TOX3 [ENSP00000219746]

CAG trinucleotide repeat-containing gene F9 protein; Transcriptional coactivator of the p300/CBP-mediated transcription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region; Trinucleotide repeat containing

Synonyms:  TOX3,  TOX3p,  hTOX3,  H3BTZ9,  J3QQQ6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM