Disease-gene associations mined from literature

Literature associating CRYM and autosomal dominant nonsyndromic deafness 2B

CRYM [ENSP00000219599]

NADP-regulated thyroid-hormone-binding protein; Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors.

Synonyms:  CRYM,  CRYM-001,  CRYM-002,  CRYM-003,  CRYM-004 ...

Linkouts:  STRING  Pharos  UniProt  OMIM