DISEASES

Disease-gene associations mined from literature

Literature associating STAG2 and laryngotracheitis

STAG2 [ENSP00000218089]

Cohesin subunit SA-2; Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis; Belongs to the SCC3 family.

Synonyms:  STAG2,  STAG2p,  hSTAG2,  B1AMS8,  B1AMS9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM