DISEASES

Disease-gene associations mined from literature

Literature associating TBL1X and ocular albinism

TBL1X [ENSP00000217964]

F-box-like/WD repeat-containing protein TBL1X; F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange; WD repeat domain containing

Synonyms:  TBL1X,  TBL1Xp,  hTBL1X,  A0A024RBV9,  C9J5F9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM