Disease-gene associations mined from literature

Literature associating CHGA and pineal region choriocarcinoma

CHGA [ENSP00000216492]

p-Glu serpinin precursor; [Pancreastatin]: Strongly inhibits glucose induced insulin release from the pancreas. [Serpinin]: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation.

Synonyms:  CHGA,  G3V2Q7,  G5E968,  P10645,  G3V2Q7p ...

Linkouts:  STRING  Pharos  UniProt  OMIM