DISEASES

Disease-gene associations mined from literature

Literature associating CERK and retinitis pigmentosa 26

CERK [ENSP00000216264]

Acylsphingosine kinase; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.

Synonyms:  CERK,  A0A024R4U8,  CERK-001,  CERK-002,  CERK-003 ...

Linkouts:  STRING  Pharos  UniProt  OMIM