DISEASES

Disease-gene associations mined from literature

Literature associating LGALS1 and chronic monocytic leukemia

LGALS1 [ENSP00000215909]

Lectin, galactoside-binding, soluble, 1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis; Endogenous ligands

Synonyms:  LGALS1,  LGALS1p,  hLGALS1,  F8WCQ5,  F8WEI7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM