DISEASES

Disease-gene associations mined from literature

Literature associating SNRPD3 and lupus erythematosus

SNRPD3 [ENSP00000215829]

Small nuclear ribonucleoprotein D3 polypeptide 18kDa; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing.

Synonyms:  SNRPD3,  SNRPD3p,  hSNRPD3,  B4DJP7,  H3BT13 ...

Linkouts:  STRING  Pharos  UniProt  OMIM