Literature associating SERPIND1 and Noonan syndrome with multiple lentigines 2
Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner; Belongs to the serpin family.
Synonyms: SERPIND1, P05546, SERPIND1-001, SERPIND1-002, HCF2 ...