Disease-gene associations mined from literature

Literature associating VCL and hypertrophic cardiomyopathy

VCL [ENSP00000211998]

Metavinculin; Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion; Belongs to the vinculin/alpha-catenin family.

Synonyms:  VCL,  A0A024QZN4,  HEL114,  P18206,  Q5JQ13 ...

Linkouts:  STRING  Pharos  UniProt  OMIM