Literature associating OSGEP and cataract 14 multiple types
t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity; Belongs to the KAE1 / TsaD family.
Synonyms: OSGEP, G3V249, G3V282, G3V425, G3V445 ...