DISEASES

Disease-gene associations mined from literature

Literature associating NME8 and primary ciliary dyskinesia 1

NME8 [ENSP00000199447]

Thioredoxin domain-containing protein 3; Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds; NME/NM23 family

Synonyms:  NME8,  NME8p,  hNME8,  C9JG62,  C9JIT0 ...

Linkouts:  STRING  Pharos  UniProt