Disease-gene associations mined from literature

Literature associating STK10 and common bile duct disease

STK10 [ENSP00000176763]

Serine/threonine-protein kinase 10; Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

Synonyms:  STK10,  STK10p,  hSTK10,  O94804,  STK10-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM