DISEASES

Disease-gene associations mined from literature

Literature associating CREB3L3 and Torrance type platyspondylic dysplasia

CREB3L3 [ENSP00000078445]

Cyclic AMP-responsive element-binding protein 3-like protein 3; Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes. Activated in response to cAMP stimulation. In vitro, binds to the cAMP response element (CRE) and box-B element. Activates transcription through box-B element. Activates transcription through CRE (By similarity). Seems to function synergistically with ATF6. In acute inflammatory response, may activate expression of acute phase response (APR) genes. May be involved in growth suppression; Basic leucine zipper proteins

Synonyms:  CREB3L3,  CREB3L3p,  hCREB3L3,  CREB3L3-001,  CREB3L3-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM