DISEASES

Disease-gene associations mined from literature

Literature associating LRRC7 and chromosome 3q29 microdeletion syndrome

LRRC7 [ENSP00000035383]

Leucine-rich repeat-containing protein 7; Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression; Belongs to the LAP (LRR and PDZ) protein family.

Synonyms:  LRRC7,  LRRC7p,  hLRRC7,  B1AKT2,  F8WE45 ...

Linkouts:  STRING  Pharos  UniProt  OMIM