DISEASES

Disease-gene associations mined from literature

Literature associating GPRC5A and lung mucoepidermoid carcinoma

GPRC5A [ENSP00000014914]

G protein-coupled receptor, class C, group 5, member A; Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Functions as a negative modulator of EGFR signaling (By similarity). May act as a lung tumor suppressor.

Synonyms:  GPRC5A,  GPRC5Ap,  hGPRC5A,  F5GWG3,  GPRC5A-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM