Literature associating M6PR and lysosomal and lipase deficiency
M6PR [ENSP00000000412]
Mannose-6-phosphate receptor (cation dependent); Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex; MRH domain containing
Synonyms: M6PR, M6PRp, hM6PR, F5GXE0, F5GXU0 ...