DISEASES

Disease-gene associations mined from literature

CDC14A disease associations

CDC14A [ENSP00000354916]

Dual specificity protein phosphatase CDC14A; Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis. Required for normal hearing . ECO:0000269|PubMed:12134069, ECO:0000269|PubMed:17488717,

Synonyms:  CDC14A,  CDC14Ap,  hCDC14A,  A0A0U1RQX7,  A0A2R8Y3W8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM