MAGEA1 disease associations
MAGEA1 [ENSP00000349085]
Melanoma-associated antigen 1; May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Synonyms: MAGEA1, MAGEA1p, hMAGEA1, P43355, P43355p ...