DISEASES

Disease-gene associations mined from literature

DYNC1H1 disease associations

DYNC1H1 [ENSP00000348965]

Cytoplasmic dynein 1 heavy chain 1; Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Plays a role in mitotic spindle assembly and metaphase plate congression . ; Belongs to the dynein heavy chain family.

Synonyms:  DYNC1H1,  DYNC1H1p,  hDYNC1H1,  A0A2R8Y542,  A0A2R8Y5T0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM