OSTN disease associations
OSTN [ENSP00000342356]
Processed Osteocrin; Hormone that acts as a regulator of dendritic growth in the developing cerebral cortex in response to sensory experience . Induced in the brain following membrane depolarization and inhibits dendritic branching in neurons of the developing cortex . Probably acts by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity); Belongs to the Osteocrin family.
Synonyms: OSTN, C9JER6, P61366, C9JER6p, hC9JER6 ...